# Slay the Spire 2 boss guides

> The fights that stop a run: attack patterns, phases, and the safest ways through. Player-made Slay the Spire 2 guides on QnA.GG.

The page: https://qna.gg/games/slay-the-spire-2/bosses. Every guide as JSON: https://qna.gg/api/guides?q=boss&game=Slay+the+Spire+2.

## Guides, most read first

- [Slay the Spire 2: Complete Guide](https://qna.gg/g/slay-the-spire-2-complete-guide-fe4c497e.md), by Qloud: All five characters, the acts and bosses, Ancients, Ascension, co-op, and the deckbuilding habits that win runs in Mega Crit's Early Access sequel. Researched September 2026 — current as of Early Access main branch…