Devil May Cry 5: Complete Guide

A guide to Devil May Cry 5 for first-timers and players chasing S ranks: how each of the four playable characters works, what to buy first, the style system, difficulty unlocks, secret missions and collectibles, Bloody Palace, and the fastest ways to farm Red Orbs.

Researched September 2026 — current as of the final PC build with the Playable Character: Vergil DLC (December 2020). Live games change; check the linked sources if something differs.

Status: DMC5 (March 8, 2019) is complete. Bloody Palace arrived as a free update in April 2019. Vergil became playable in the Special Edition (PS5/Xbox Series X|S, November 2020) and as the Playable Character: Vergil DLC on PC (December 15, 2020). Special Edition extras like Turbo Mode and Legendary Dark Knight difficulty are not in the standard PC version. Season 2 of Netflix's Devil May Cry animated series premiered on May 12, 2026, so expect newcomers in the community.

Quick Start

  1. Three campaigns in one. The 20 missions rotate between Nero, V and Dante. On some missions you choose which character to play.
  2. Buy abilities with Red Orbs at Nico's van or a Divinity Statue. Early buys make a huge difference.
  3. Get Style points by varying your moves. Repeating one attack drops your rank. Mix weapons, guns and styles.
  4. Taunt (default: a dedicated button) builds style and Devil Trigger gauge when there's no danger.
  5. Blue Orbs raise max health and Purple Orbs raise Devil Trigger. Blue Orb Fragments (four per orb) are hidden in missions.
  6. Gold Orbs revive you on the spot (Red Orbs can also buy a continue). It can cost you a top mission rank, but it's better than a restart.
  7. Difficulty unlocks: Human and Devil Hunter are available from the start. Clearing the story unlocks Son of Sparda, and beating that unlocks Dante Must Die. The gimmick modes Heaven or Hell (everything dies in one hit, including you) and Hell and Hell (you die in one hit) unlock later in the chain.
  8. Use the Auto Assist option (Human difficulty) if you want to see the story. It turns mashing into combos.
  9. Secret Missions are hidden in the story missions. There are 12, and they reward Blue Orb Fragments.
  10. Replay missions with new abilities to find missed collectibles and improve ranks.

The Style Meter

Characters

Nero

V

Dante

Vergil (DLC)

Early Shop Priorities

Character Buy first
Nero Streak, Split, more Devil Breaker slots, Exceed upgrades
V Griffon and Shadow basic combos, Cane attacks, faster familiar recovery
Dante Stinger (Rebellion), Swordmaster moves, Trickster dash upgrades, Royal Guard Release
All Blue Orbs (health) when they appear in the shop, and Purple Orbs (Devil Trigger)

Tip: you can Rebuy (refund) abilities at no loss, so experimenting is free.

Missions, Collectibles and Secrets

Bosses (no spoilers on order)

The game's major bosses include Goliath, Artemis, Cavaliere Angelo, Elder Geryon Knight, Gilgamesh, Malphas, Nidhogg, King Cerberus and Urizen, plus more story-critical encounters later. For each:

Bloody Palace

Red Orb Farming

Common Mistakes to Avoid

Advanced Tips

FAQ

Is the Vergil DLC worth it? Yes, if you enjoyed the game. He has a full campaign run of all 20 missions and Bloody Palace, with a unique playstyle.

How do I unlock harder difficulties? Clear the story (Human or Devil Hunter) to unlock Son of Sparda, then beat that to unlock Dante Must Die. Heaven or Hell and Hell and Hell unlock further along the chain.

How many Secret Missions are there? Twelve. They're hidden in story missions and reward Blue Orb Fragments.

Does the PC version have Legendary Dark Knight or Turbo mode? No. Those are Special Edition features on PS5 and Xbox Series X|S.

Which character should I main in Bloody Palace? Dante, for the most tools and safety.

Do I need to play the older games first? It helps with the story (DMC3, DMC4), but DMC5 includes a recap video in the menu.

Sources